Reductive Hydroformylation of Isosorbide Diallyl Ether

Jérémy Ternel (1) , Adrien Lopes (1) , Mathieu Sauthier (1) , Clothilde Buffe (2) , Vincent Wiatz (2) , Hervé Bricout (3) , Sébastien Tilloy (3) , Eric Monflier (3)

1 UCCS - Unité de Catalyse et Chimie du Solide - UMR 8181
2 ROQUETTE Frères
3 UCCS Équipe Catalyse Supramoléculaire

Isosorbide and its functionalized derivatives have numerous applications as bio-sourced building blocks. In this context, the synthesis of diols from isosorbide diallyl ether by hydrohydroxymethylation reaction is of extreme interest. This hydrohydroxymethylation, which consists of carbon-carbon double bonds converting into primary alcohol functions, can be obtained by a hydroformylation reaction followed by a hydrogenation reaction. In this study, reductive hydroformylation was achieved using isosorbide diallyl ether as a substrate in a rhodium/amine catalytic system. The highest yield in bis-primary alcohols obtained was equal to 79%.

Domains: Catalysis; Chemical Sciences

Jérémy Ternel, Adrien Lopes, Mathieu Sauthier, Clothilde Buffe, Vincent Wiatz, et al.. Reductive Hydroformylation of Isosorbide Diallyl Ether. Molecules, 2021, 26 (23), pp.7322. ⟨10.3390/molecules26237322⟩. ⟨hal-03675976⟩