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Journal articles
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells
Marion Clé
1
Orianne Constant
1
Jonathan Barthelemy
1
Caroline Desmetz
2
Marie France Martin
3
Lina Lapeyre
3
Daniel Cadar
4
Giovanni Savini
5
Liana Teodori
5
Federica Monaco
5
Jonas Schmidt-Chanasit
4, 6
Juan-Carlos Saiz
7
Gaëlle Gonzales
8
Sylvie Lecollinet
8
Cécile Beck
8
Fabien Gosselet
9
Philippe van de Perre
1, 10
Vincent Foulongne
1, 10
Sara Salinas
1
Yannick Simonin
1, *
*
Corresponding author
Marion Clé 1
relator_co_first_author
Orianne Constant 1
relator_co_first_author
Jonathan Barthelemy 1
Author
Caroline Desmetz 2
Author
Liana Teodori 5
Author
Federica Monaco 5
Author
Jonas Schmidt-Chanasit 4, 6
Author
Juan-Carlos Saiz 7
Author
Gaëlle Gonzales 8
Author
Sylvie Lecollinet 8
Author
Cécile Beck 8
Author Employer institution : Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail IdHAL : cecile-beck
Fabien Gosselet 9
Author IdHAL : fabgoss ORCID : https://orcid.org/0000-0002-0481-5026
Philippe van de Perre 1, 10
Author
Vincent Foulongne 1, 10
Author
Sara Salinas 1
Author
Yannick Simonin 1
Correspondent author IdHAL : yannick-simonin ORCID : https://orcid.org/0000-0002-3475-1369
1
Pathogénèse et contrôle des infections chroniques (PCCI) (Hôpital Arnaud de Villeneuve - 371 avenue Doyen Gaston Giraud 34295 Cedex 5 Montpellier. - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U1058 (101, rue de Tolbiac, 75013 Paris - France)
- CHU Montpellier - Centre Hospitalier Universitaire de Montpellier (France)
- UM - Université de Montpellier (163 rue Auguste Broussonnet - 34090 Montpellier - France)
2
BC2M - Biocommunication en Cardio-Métabolique (EA 7288, Université de Montpellier, Montpellier - France)
- UM - Université de Montpellier : UM 101 (163 rue Auguste Broussonnet - 34090 Montpellier - France)
3
IRIM - Institut de Recherche en Infectiologie de Montpellier (UMR 9004, 1919 Route de Mende - 34293 Montpellier - France)
- UM - Université de Montpellier (163 rue Auguste Broussonnet - 34090 Montpellier - France)
- CNRS - Centre National de la Recherche Scientifique : UMR9004 (France)
4
BNITM - Bernhard Nocht Institute for Tropical Medicine - Bernhard-Nocht-Institut für Tropenmedizin [Hamburg, Germany] (Bernhard-Nocht-Straße 74, 20359 Hamburg. - Germany)
5
IZSAM - Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise Guiseppe Caporale (Campo Boario
64100 Teramo - Italy)
- Partenaires INRAE (Cette structure regroupe l'ensemble des structures créées pour la reprise des données ProdInra - France)
6
Department of Mathematics - University of Hamburg (Bundesstraße 55 D-20146 Hamburg - Germany)
- University of Hamburg (Mittelweg 177, 20148 Hamburg - Germany)
7
INIA - Instituto Nacional de Investigación Agropecuaria (Andes 1365 - piso 12 CP. 11100 Montevideo - Uruguay - Uruguay)
8
VIRO - Virologie UMR1161 (7 avenue du Général de Gaulle 94704 MAISONS-ALFORT CEDEX - France)
- ENVA - École nationale vétérinaire d'Alfort (7 avenue du Général de Gaulle - 94700 Maisons Alfort - France)
- ANSES - Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (14 rue Pierre et Marie Curie 94701 MAISONS-ALFORT Cedex - France)
- INRAE - Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement : UMR1161 (France)
9
LBHE - Laboratoire de la Barrière Hémato-Encéphalique (Faculté Jean Perrin, Rue Jean Souvraz, 62300 LENS - France)
- UA - Université d'Artois : UR2465 (9 rue du Temple - BP 10665 - 62030 Arras cedex - France)
10
CHU Montpellier (371, avenue du Doyen Gaston Giraud 34295 MONTPELLIER cedex 5 - France)
- CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier] (191 avenue du doyen Gaston Giraud 34295 Montpellier cedex 5 - France)
Abstract : Usutu virus (USUV) is an emerging neurotropic arthropod-borne virus recently involved in massive die offs of wild birds predominantly reported in Europe. Although primarily asymptomatic or presenting mild clinical signs, humans infected by USUV can develop neuroinvasive pathologies (including encephalitis and meningoencephalitis). Similar to other flaviviruses, such as West Nile virus, USUV is capable of reaching the central nervous system. However, the neuropathogenesis of USUV is still poorly understood, and the virulence of the specific USUV lineages is currently unknown. One of the major complexities of the study of USUV pathogenesis is the presence of a great diversity of lineages circulating at the same time and in the same location.
Document type :
Journal articles
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https://hal-univ-artois.archives-ouvertes.fr/hal-03126852
Contributor : Virginie Justin-Labonne Connect in order to contact the contributor
Submitted on : Wednesday, February 3, 2021 - 4:28:11 PM
Last modification on : Friday, October 22, 2021 - 12:38:01 PM
Contributor : Virginie Justin-Labonne Connect in order to contact the contributor
Submitted on : Wednesday, February 3, 2021 - 4:28:11 PM
Last modification on : Friday, October 22, 2021 - 12:38:01 PM
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2021_Clé_J Neuroinflammation....
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Distributed under a Creative Commons Attribution 4.0 International License
Identifiers
- HAL Id : hal-03126852, version 1
- DOI : 10.1186/s12974-020-02060-4
- PUBMED : 33407600
- PUBMEDCENTRAL : PMC7789689
Collections
INSERM | LBHE | INRAE | UNIV-MONTPELLIER | BS | CNRS | UNIV-ARTOIS | ANSES | ANR | PCCI
Citation
Marion Clé, Orianne Constant, Jonathan Barthelemy, Caroline Desmetz, Marie France Martin, et al.. Differential neurovirulence of Usutu virus lineages in mice and neuronal cells. Journal of Neuroinflammation, BioMed Central, 2021, 18 (1), ⟨10.1186/s12974-020-02060-4⟩. ⟨hal-03126852⟩
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